Chemical Assessing according to Legislation En- hancing the In-silico Documentation and Safe use

Project abstract

CALEIDOS is about implementing European policies for the regulation of chemicals (REACH).
It approaches a huge knowledge gap in REACH, which mentions non-testing methods (NTM) and requires that any effort has to be done to avoid animal use, but does not identify which methods to use.
Main objectives are:


• verify the possible use of NTM for REACH

• study 6 environmental and human toxicity endpoints

• integrate different methods achieving superior performance

• release validated and open access integrated models for those endpoints

• promote NTM for legislative purposes
Partners are Mario Negri Institute (Italy), INERIS (France), Umweltbundesamt (Austria), ISPRA (Italy), Direcao General de Saude (Portugal), Polimi (Italy), Universitat Rovira i Virgili (Spain), INFOTOX (Portugal), Centro REACH (Italy).